The combination of phentermine and topiramate is very popular for weight loss management. It is also called as phentermine hydrochloride topiramate. Qsymia is the well known brand name for phentermine and topiramate combination. When it comes to weight loss one can achieve additional benefits when they combine phentermine and topiramate. Phentermine and topiramate together is also effective in suppressing the appetite.

The Qsymia brand name can be purchased only through prescription. This is because it is classified into Schedule IV class controlled substance.

Results of this combination:

Phentermine has the ability to play a major role in the releasing catecholamine in the hyphothalamus. This results in reducing the appetite. So, this helps in decreasing the calorie intake in an individual. Even though the combination of phentermine and topiramate has gained popularity in the field of weight loss management, it is yet to understand the reactions of topiramate when combined with phentermine. but it is known that topiramate has the ability to promote satiety and a sense of fullness in an individual. This is because of its reactions on enzyme functions and neurotransmitters.

Phentermine and topiramate together

When the combination of Phentermine and topiramate together is followed along with planned diet and proper physical activities can make miracles in weight loss management.


If used as per instructions by a bariatric specialist or a doctor the combination of phentermine and topiramate is considered safe for use. But there are many factors that decide the safety. Some of them are eating behaviors, eating disorders, exercise levels, ability of an individual adhere to dietary requirements, his age, and even his overall health condition.

The combination of phentermine and topiramate is available in the form of capsules with varying milligram strengths. Some of them are

  • 15 mg phen/ 92 mg of topiramate
  • 11.25 mg of phen/ 69 mg of topiramate
  • 3.75 mg of phen/ 23 mg topiramate

There combinations are suitable for individuals with BMI of 30 kg per square meter or more. With this body mass index individual is classified as obese. Individual is considered overweight if the body mass index is over 27 kg per square meter.


Milligram dosage can be increased gradually by looking at the results. To evaluate the weight loss efforts one may take 12 weeks of usage. By this time there must be significant changes otherwise either the physician will insist to discontinue the medicine or they may suggest higher dose that is 11.25 mg of phentermine / 69 mg topiramate.

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